
https://pubmed.ncbi.nlm.nih.gov/29322876/
Publicado en: CARTILAGE Abstract. In the process of cell division, the extremes of the eukaryotic chromosomes are progressively shortening, and this phenomenon ...
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In Vivo Target Gene Activation via CRISPR/Cas9- Mediated Trans-epigenetic Modulation
Publicado en: Cell Summary Current genome-editing systems generally rely on inducing DNA double-strand breaks (DSBs). This may limit their utility in ...
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Cartilage Defect Treatment Using High-Density Autologous Chondrocyte Implantation: Two-Year Follow-up
Publicado en: Cartilage Objective. The aim of this work was to study the short- and mid-term effectiveness and safety of ...
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Interspecies chimerism with mammalian pluripotent stem cells
Publicado en: Cell Interspecies blastocyst complementation enables organ-specific enrichment of xenogenic pluripotent stem cell (PSC) derivatives. Here, we establish a versatile blastocyst complementation platform ...
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In vivo genome editing via CRISPR-Cas9 mediated homology-independent targeted integration
Publicado en: Nature Targeted genome editing via engineered nucleases is an exciting area of biomedical research and holds potential for ...
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