Publicado en: M.OJ Clin Med Case Rep
Rheumatoid arthritis is an inflammatory condition that causes a negative effect in patient well-being. Fibroblast growth factor participates in the pathology of rheumatoid arthritis through its proliferative, inflammatory and angiogenic activities. Dobesilate, an inhibitor of fibroblast growth factor shows marked anti-proliferative, anti-inflammatory, and anti-angiogenic activities. Our study shows that intraarticular application of dobesilate is effective in reducing symptoms and signs in patients with chronic knee rheumatoid arthritis.
Cuevas P, Fernández-Jaén T, Guillen P, Angulo J, Giménez-Gallego G (2016) “Intraarticular administration of Dobesilate for the Treatment of Knee Rheumatoid Arthritis”. M.OJ Clin Med Case Rep 5(1):00119 (2016)